Molecular docking and pharmacokinetic properties of chrysin, indole-3-carbinol, and curcumin in the biological context of Plasmodium falciparum 3D7

The findings predict that the chrysin compound exhibits better affinity with P. falciparum proteins, suggesting that this compound can effectively interact with specific targets within the parasite. It also highlights the favorable electrostatic interactions that contribute to its pharmacological effectiveness as an acetyl-CoA reductase inhibitor.