A Rare Case of Non-cirrhotic Acute Portal Vein Thrombosis With Gallbladder Infarction

Non-cirrhotic portal vein thrombosis (PVT) is rare, and early initiation of anticoagulation therapy is crucial for recanalization and preventing complications. A man in his 50s presented to the emergency department with acute back pain. His vital signs and laboratory results were normal, showing no signs of infection. An initial computed tomography (CT) scan with intravenous contrast in the arterial phase showed no abnormalities. However, on the third day, a CT scan in the late phase confirmed PVT in the left branch, along with gallbladder infarction. This case highlights the limitations of arterial-phase CT in diagnosing acute PVT, which often extends to the splenic vein or superior mesenteric venous arches and may lead to intestinal infarction, although gallbladder infarctions remain rare.

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Publication Details

Journal
Cureus
Published
2025-02-13
DOI
https://doi.org/10.7759/cureus.78965
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

A Rare Case of Non-cirrhotic Acute Portal Vein Thrombosis With Gallbladder Infarction

Yo Matsuo, Mitsunobu Toyosaki, Junichi Sasaki, Mao Tsukadaira
Cureus
Liver Disease and Transplantation
article

A Rare Case of Non-cirrhotic Acute Portal Vein Thrombosis With Gallbladder Infarction

Yo Matsuo, Mitsunobu Toyosaki, Junichi Sasaki, Mao Tsukadaira
article en

Abstract

Non-cirrhotic portal vein thrombosis (PVT) is rare, and early initiation of anticoagulation therapy is crucial for recanalization and preventing complications. A man in his 50s presented to the emergency department with acute back pain. His vital signs and laboratory results were normal, showing no signs of infection. An initial computed tomography (CT) scan with intravenous contrast in the arterial phase showed no abnormalities. However, on the third day, a CT scan in the late phase confirmed PVT in the left branch, along with gallbladder infarction. This case highlights the limitations of arterial-phase CT in diagnosing acute PVT, which often extends to the splenic vein or superior mesenteric venous arches and may lead to intestinal infarction, although gallbladder infarctions remain rare.

CureusVol. 17(2)
Keio University (JP), Fundación Universitaria San Alfonso (CO)
Good health and well-being
Openalex Percentile: Top 96%
Liver Disease and Transplantation
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