Spotlight on the Unusual: A Case Report of Adrenal Angiosarcoma Presenting as an Abdominal Mass

This case discusses the challenges of diagnosing adrenal angiosarcoma, a rare and aggressive malignancy that constitutes an exceptionally small proportion of adrenal tumors. Angiosarcomas originate from blood or lymphatic vessel endothelium, with soft tissue and cutaneous forms being more prevalent than those arising in visceral organs such as the adrenal glands. This report describes a 47-year-old female patient who presented with a large right adrenal mass identified through imaging and was subsequently diagnosed with primary adrenal angiosarcoma. This disease may remain asymptomatic or present with nonspecific symptoms, making early detection challenging. Prompt identification and surgical management are essential, as the tumor exhibits a high propensity for aggressive behavior and metastatic spread. While no standardized treatment guidelines exist, adrenalectomy and systemic therapy are commonly employed strategies. Prognosis remains unfavorable, often influenced by tumor size, necrosis, and metastatic involvement at diagnosis. This case highlights the importance of accurate diagnostic methods and early intervention to enhance patient outcomes.

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Publication Details

Journal
Cureus
Published
2025-02-13
DOI
https://doi.org/10.7759/cureus.78968
Citations
1
Primary Topic
Vascular Tumors and Angiosarcomas
Type
article
Field-Weighted Citation Impact
1.05
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article

Spotlight on the Unusual: A Case Report of Adrenal Angiosarcoma Presenting as an Abdominal Mass

Laurianne Pech, Ermilo Echeverría-Ortegón, Javier Casillas, Isabella Canto
1 citations
Cureus
Vascular Tumors and Angiosarcomas
1.05
article

Spotlight on the Unusual: A Case Report of Adrenal Angiosarcoma Presenting as an Abdominal Mass

Laurianne Pech, Ermilo Echeverría-Ortegón, Javier Casillas, Isabella Canto
article en
1 citations

Abstract

This case discusses the challenges of diagnosing adrenal angiosarcoma, a rare and aggressive malignancy that constitutes an exceptionally small proportion of adrenal tumors. Angiosarcomas originate from blood or lymphatic vessel endothelium, with soft tissue and cutaneous forms being more prevalent than those arising in visceral organs such as the adrenal glands. This report describes a 47-year-old female patient who presented with a large right adrenal mass identified through imaging and was subsequently diagnosed with primary adrenal angiosarcoma. This disease may remain asymptomatic or present with nonspecific symptoms, making early detection challenging. Prompt identification and surgical management are essential, as the tumor exhibits a high propensity for aggressive behavior and metastatic spread. While no standardized treatment guidelines exist, adrenalectomy and systemic therapy are commonly employed strategies. Prognosis remains unfavorable, often influenced by tumor size, necrosis, and metastatic involvement at diagnosis. This case highlights the importance of accurate diagnostic methods and early intervention to enhance patient outcomes.

CureusVol. 17(2)
Jackson Memorial Hospital (US), Universidad Marista de Mérida (MX)
Zero hunger
Openalex Percentile: Top 25%
Vascular Tumors and Angiosarcomas
1.05
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Spotlight on the Unusual: A Case Report of Adrenal Angiosarcoma Presenting as an Abdominal Mass — Laurianne Pech, Ermilo Echeverría-Ortegón, et al. · Cureus (2025) | TGRS Research Map | TGRS