Investigation of Gait Characteristics and Kinematic Deviations in Rare Genetic Disorders with Instrumented Gait Analysis
The current study reveals differences in gait characteristics from typical functional gait in rare genetic disorders. DS-Crouch, DS-NonCrouch and HVDAS display a more impaired gait from a biomechanical perspective than TSC. The variability of clinical and genetic features might explain heterogeneity in gait deviations and should be further explored.
Authors
- Anna Jansen (ORCID: https://orcid.org/0000-0002-3835-2824)
- Esra Kınacı‐Biber (ORCID: https://orcid.org/0000-0002-2977-0928)
- Patricia Van de Walle (ORCID: https://orcid.org/0000-0001-8948-8927)
- An‐Sofie Schoonjans (ORCID: https://orcid.org/0000-0001-7545-518X)
- R. Frank Kooy (ORCID: https://orcid.org/0000-0003-2024-0485)
- Ann Hallemans (ORCID: https://orcid.org/0000-0003-4101-5279)
- Anke Van Dijck (ORCID: https://orcid.org/0000-0002-6713-2943)
- Lis Gys
Institutions
- University of Antwerp (BE)
- Antwerp University Hospital (BE)
- Düzce Üniversitesi (TR)
- Hacettepe University (TR)
Publication Details
- Journal
- Journal of Intellectual Disability Research
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1111/jir.13218
- Citations
- 3
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 4.88
Funders
- University of Pennsylvania
- Fonds Wetenschappelijk Onderzoek
- Universiteit Antwerpen
- Vlaamse regering