Preoperative Peripheral Blood Serotonin and Kynurenine Levels Are Associated With Oncological Outcomes in Glioblastoma IDH-wt Patients
This study highlights an intriguing association between the degradation of TRP along the KP and SP and median survival times in GBM. Decreased KYN, 5-HTP, and 5-HT levels were associated with shorter OS.
Authors
- Stefano Comai (ORCID: https://orcid.org/0000-0002-5686-7194)
- Francesca Roncelli (ORCID: https://orcid.org/0000-0001-9990-1076)
- Antonella Bertazzo
- Silvia Snider
- Pierfrancesco De Domenico (ORCID: https://orcid.org/0000-0003-3330-162X)
- Filippo Gagliardi (ORCID: https://orcid.org/0000-0002-2296-1764)
- Pietro Mortini (ORCID: https://orcid.org/0000-0003-2320-2281)
- Sofia Nasini (ORCID: https://orcid.org/0000-0002-5821-9684)
- Angela Ruban (ORCID: https://orcid.org/0000-0003-1091-8854)
- Benedetta Barzon
Institutions
- University of Padua (IT)
- Vita-Salute San Raffaele University (IT)
- Tel Aviv University (IL)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- McGill University (CA)
Publication Details
- Journal
- International Journal of Tryptophan Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1177/11786469241312475
- Citations
- 4
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.31