Real-world experience of renal outcomes and management of PrEP users with estimated glomerular filtration rates less than 60 mL/min/1.73 m<sup>2</sup>
This retrospective service evaluation reviews practical measures for pre-exposure prophylaxis (PrEP) users with estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m<sup>2</sup> Of 35 724 PrEP users, 361 had an eGFR <60 mL/min/1.73 m<sup>2</sup>, of whom 16% required non-tenofovir disoproxil/emtricitabine PrEP formulations. Majority of cases required simple and conservative management, with repeat sampling and/or stopping of the supplements and/or recreational drugs.
Authors
- Jonathan Joseph Goodfellow
- Victoria Tittle
- Marta Boffito (ORCID: https://orcid.org/0000-0002-2213-1103)
- Sheel Patel (ORCID: https://orcid.org/0009-0005-7873-6653)
- Nicolò Girometti (ORCID: https://orcid.org/0000-0002-2960-2748)
- Sheena McCormack (ORCID: https://orcid.org/0000-0002-7829-1325)
- Rachael M. Jones (ORCID: https://orcid.org/0000-0003-1611-7900)
- Stephen Cole
Institutions
- Chelsea and Westminster Hospital NHS Foundation Trust (GB)
- University College London (GB)
Publication Details
- Journal
- Sexually Transmitted Infections
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1136/sextrans-2024-056411
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.00