Infants needed to immunise with nirsevimab to prevent one RSV hospitalisation, Spain, 2023/24 season

Using real-life data from Spain between October 2023 and March 2024, the number needed to immunise (NNI) with nirsevimab and the cost to prevent one RSV hospitalisation were estimated at 90 infants (95% CI: 77-108) and 19,700 EUR for catch-up immunisation, and 41 infants (95% CI: 35-50) and 9,000 EUR for at-birth immunisation. By month of birth, NNI and cost were lowest in infants born shortly before the RSV epidemic peak, with impact decreasing gradually for earlier or later births.

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Publication Details

Journal
Eurosurveillance
Published
2025-02-13
DOI
https://doi.org/10.2807/1560-7917.es.2025.30.6.2500040
Citations
8
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
10.83
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article

Infants needed to immunise with nirsevimab to prevent one RSV hospitalisation, Spain, 2023/24 season

Olivier G. Nunez, Susana Monge, Roberto Pastor‐Barriuso
8 citations
Eurosurveillance
Respiratory viral infections research
10.83
article

Infants needed to immunise with nirsevimab to prevent one RSV hospitalisation, Spain, 2023/24 season

Olivier G. Nunez, Susana Monge, Roberto Pastor‐Barriuso
article en
8 citations

Abstract

Using real-life data from Spain between October 2023 and March 2024, the number needed to immunise (NNI) with nirsevimab and the cost to prevent one RSV hospitalisation were estimated at 90 infants (95% CI: 77-108) and 19,700 EUR for catch-up immunisation, and 41 infants (95% CI: 35-50) and 9,000 EUR for at-birth immunisation. By month of birth, NNI and cost were lowest in infants born shortly before the RSV epidemic peak, with impact decreasing gradually for earlier or later births.

EurosurveillanceVol. 30(6)
Instituto de Salud Carlos III (ES), Centre for Biomedical Network Research on Rare Diseases (ES), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES), Individual Differences (US)
Good health and well-being
Openalex Percentile: Top 2%
Respiratory viral infections research
10.83
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