Autoimmune Thyroid Disorder in a 15-Year-Old Female with Concurrent Dengue: A Case Study

We report a case of a 15-year-old female who presented with high grade fever and thrombocytopenia, slightly elevated creatinine levels, initially diagnosed with dengue fever.Elevated LDH and Ferritin level indicated the severity of dengue, yet after 7 days of treatment, her elevated creatinine levels remained unchanged, prompting further investigation.Thyroid function tests revealed severe hypothyroidism with a TSH level exceeding 250 IU/mL and antibody testing (Anti-Tg and Anti-TPO) confirmed autoimmune thyroiditis (Hashimoto's Thyroiditis).This case highlights the importance of considering underlying autoimmune conditions in patients with persistent abnormal laboratory findings, even in the context of infectious diseases such as dengue.After initiating thyroid hormone replacement therapy, the patient's creatinine levels returned to normal and she is expected to lead a healthy life with ongoing management.Early detection and treatment of thyroid disorders are crucial to preventing further complications, particularly in patients with coexisting conditions.This case emphasizes the need for thorough diagnostic evaluation in patients whose clinical abnormalities don't resolve with initial treatment modalities.

Authors

Publication Details

Journal
International Journal of Pharmaceutical Sciences Review and Research
Published
2024-12-01
DOI
https://doi.org/10.47583/ijpsrr.2024.v84i12.006
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Autoimmune Thyroid Disorder in a 15-Year-Old Female with Concurrent Dengue: A Case Study

Rahul Gopalakrishnan, Lydia Jeris W, Seethalakshmi S, Vijayakumar PG
International Journal of Pharmaceutical Sciences Review and Research
Thyroid Disorders and Treatments
article

Autoimmune Thyroid Disorder in a 15-Year-Old Female with Concurrent Dengue: A Case Study

Rahul Gopalakrishnan, Lydia Jeris W, Seethalakshmi S, Vijayakumar PG
article en

Abstract

We report a case of a 15-year-old female who presented with high grade fever and thrombocytopenia, slightly elevated creatinine levels, initially diagnosed with dengue fever.Elevated LDH and Ferritin level indicated the severity of dengue, yet after 7 days of treatment, her elevated creatinine levels remained unchanged, prompting further investigation.Thyroid function tests revealed severe hypothyroidism with a TSH level exceeding 250 IU/mL and antibody testing (Anti-Tg and Anti-TPO) confirmed autoimmune thyroiditis (Hashimoto's Thyroiditis).This case highlights the importance of considering underlying autoimmune conditions in patients with persistent abnormal laboratory findings, even in the context of infectious diseases such as dengue.After initiating thyroid hormone replacement therapy, the patient's creatinine levels returned to normal and she is expected to lead a healthy life with ongoing management.Early detection and treatment of thyroid disorders are crucial to preventing further complications, particularly in patients with coexisting conditions.This case emphasizes the need for thorough diagnostic evaluation in patients whose clinical abnormalities don't resolve with initial treatment modalities.

International Journal of Pharmaceutical Sciences Review and ResearchVol. 84(12)
Openalex Percentile: Top 60%
Thyroid Disorders and Treatments
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