A surrogate in vitro experimental model for off-label drug repurposing: inhibitory effect of montelukast on bovine respiratory syncytial virus replication
MLS demonstrated a dose-dependent antiviral effect against BRSV, achieving 99% viral inhibition properties in MDBK cells. These promising results warrant further investigation into the antiviral mechanisms of MLS.
Authors
- Cüneyt Tamer (ORCID: https://orcid.org/0000-0003-3240-8425)
- Semra Okur‐Gumusova
- Hüseyin Baskın (ORCID: https://orcid.org/0000-0003-3237-267X)
- Harun Albayrak (ORCID: https://orcid.org/0000-0002-4468-2790)
- Bahadır Müftüoğlu (ORCID: https://orcid.org/0000-0002-7789-1038)
- Vahide Bayrakal (ORCID: https://orcid.org/0000-0003-0670-2575)
- Gerald Barry (ORCID: https://orcid.org/0000-0002-6262-3380)
- Hanne Nur Kuruçay (ORCID: https://orcid.org/0000-0001-5157-2090)
- Ahmed Eısa Elhag (ORCID: https://orcid.org/0000-0002-0738-1825)
- Emre Özan (ORCID: https://orcid.org/0000-0001-9872-8152)
- Seda Gözel (ORCID: https://orcid.org/0000-0003-2976-5245)
- Zafer Yazıcı (ORCID: https://orcid.org/0000-0002-2806-7878)
- Mahir İğde
Institutions
- University College Dublin (IE)
- Dokuz Eylül University (TR)
- Ondokuz Mayıs University (TR)
- Istinye University (TR)
- Institute of Biochemistry and Biophysics, Polish Academy of Sciences (PL)
- Gadarif University (SD)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1186/s12985-025-02647-4
- Citations
- 1
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.35