Tryptophan-induced effects on the behavior and physiology of aging in tryptophan hydroxylase-2 heterozygous mice C57BL/6N
Trp exhibited genotype-specific effects, with HET mice showing anabolic, hepatoprotective, and neuropsychiatric changes. These findings highlight Trp's potential in neuro-nutrition for conditions like depression and cognitive decline. Further studies are needed to explore Trp's metabolic pathways and their implications for personalized dietary interventions.
Authors
- Anastasiya Kibitkina (ORCID: https://orcid.org/0000-0001-6934-7342)
- Galina S. Tolmacheva (ORCID: https://orcid.org/0000-0001-9937-320X)
- S. Yu. Karabanov (ORCID: https://orcid.org/0000-0002-1688-4045)
- Е.R. Vasilevskaya (ORCID: https://orcid.org/0000-0002-4752-3939)
- V.A. Pchelkina (ORCID: https://orcid.org/0000-0001-8923-8661)
- Elena Kotenkova (ORCID: https://orcid.org/0000-0003-1864-8115)
- Liliya Fedulova (ORCID: https://orcid.org/0000-0003-3573-930X)
- E. K. Polishchuk (ORCID: https://orcid.org/0000-0003-2719-9649)
Institutions
- Moscow Institute of Physics and Technology (RU)
- All-Russian Scientific Research Institute of Refrigeration Industry (RU)
Publication Details
- Journal
- Veterinary World
- Published
- 2025-02-01
- DOI
- https://doi.org/10.14202/vetworld.2025.296-310
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00