Impact of HIV Status on Group B Streptococcus Colonization and Antibody Responses in Serum and Vaginal Mucosa

Despite fluctuating GBS colonization, antibody levels remained stable over 12 weeks. The level of CPS-Ia-specific IgG in serum was lower in women with HIV than in those without HIV. Vaginal CPS-specific IgG was not measurable in 81% of individuals with HIV.

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Publication Details

Journal
The Pediatric Infectious Disease Journal
Published
2025-02-01
DOI
https://doi.org/10.1097/inf.0000000000004659
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
0.00

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article

Impact of HIV Status on Group B Streptococcus Colonization and Antibody Responses in Serum and Vaginal Mucosa

John S. Tregoning, Juliet Nsimire Sendagala, Camille Barro, Mary Kyohere et al.
The Pediatric Infectious Disease Journal
Neonatal and Maternal Infections
article

Impact of HIV Status on Group B Streptococcus Colonization and Antibody Responses in Serum and Vaginal Mucosa

John S. Tregoning, Juliet Nsimire Sendagala, Camille Barro, Mary Kyohere, Tom Hall, Olwenn Daniel, Kirsty Le Doaré, Madeleine Cochet, Scott Richard Beach, Esther Imede, Joannah Nalwoga, Thushani Tharmarasa
article en

Abstract

Despite fluctuating GBS colonization, antibody levels remained stable over 12 weeks. The level of CPS-Ia-specific IgG in serum was lower in women with HIV than in those without HIV. Vaginal CPS-specific IgG was not measurable in 81% of individuals with HIV.

The Pediatric Infectious Disease JournalVol. 44(2S)
Defence Science and Technology Laboratory (GB), St George's, University of London (GB), MUJHU Research Collaboration (UG), City St George's, University of London (GB), Imperial College London (GB), Makerere University (UG), Uganda Virus Research Institute (UG)
Medical Research Council
Good health and well-being
Openalex Percentile: Top 96%
Neonatal and Maternal Infections
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Impact of HIV Status on Group B Streptococcus Colonization and Antibody Responses in Serum and Vaginal Mucosa — John S. Tregoning, Juliet Nsimire Sendagala, et al. · The Pediatric Infectious Disease Journal (2025) | TGRS Research Map | TGRS