Comparative Analysis of Transplacental SARS-CoV-2 Antibody Transfer in Pregnancy Phenotypes With Pre-eclampsia and/or Small-for-gestational-age Infants
We analyzed paired maternal and cord samples for anti-spike protein antibody levels from pregnant individuals who received at least 2 doses of an mRNA COVID-19 vaccine before delivery and who had diagnoses consistent with placental dysfunction including pre-eclampsia and/or small-for-gestational-age infants. Our findings reveal similar median maternal and cord antibody levels across all groups despite the presence of these pregnancy complications.
Authors
- Alisa Kachikis (ORCID: https://orcid.org/0000-0003-0358-5107)
- Linda O. Eckert (ORCID: https://orcid.org/0000-0002-1357-8405)
- Lindsay Cheu (ORCID: https://orcid.org/0000-0002-5411-0446)
- Janet A. Englund (ORCID: https://orcid.org/0000-0003-1134-4178)
- Stephen A. McCartney (ORCID: https://orcid.org/0000-0003-1102-6778)
- Mindy Pike (ORCID: https://orcid.org/0000-0002-7153-868X)
- Sharon Kung
- Sriya Paluvayi
Institutions
- Seattle Children's Hospital (US)
- University of Washington (US)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1097/inf.0000000000004642
- Primary Topic
- COVID-19 Impact on Reproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00