The Causal Role of Immune Cell Phenotypes and Inflammatory Factors in Childhood Asthma: Evidence From Mendelian Randomization
This study provides a comprehensive investigation into the complex interplay between immune system dysregulation and childhood asthma. By identifying specific inflammatory factors and immune cell phenotypes linked to asthma risk and protection, the findings offer valuable insights into disease pathogenesis. While these results highlight potential targets for precision-based therapeutic interventions, further research is needed to validate these associations and translate them into clinical applications.
Authors
- Zhoushan Feng (ORCID: https://orcid.org/0000-0002-5400-7852)
- Sen Qiao (ORCID: https://orcid.org/0000-0002-5982-1386)
- Fan Wu (ORCID: https://orcid.org/0000-0003-3615-1217)
- Bing Han (ORCID: https://orcid.org/0000-0003-4584-1092)
- Xiaochun Chen (ORCID: https://orcid.org/0000-0002-2665-4155)
- Mei Jia
- Xiaohong Wu (ORCID: https://orcid.org/0000-0002-9983-7972)
- Chunhong Jia (ORCID: https://orcid.org/0009-0003-9668-2586)
Institutions
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- Shenzhen Second People's Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Pediatric Pulmonology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/ppul.27480
- Citations
- 3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 5.45