Mitochondrial Dysfunction: Unraveling the Elusive Biology Behind Anti-TNF Response During Ulcerative Colitis
Our results highlight the involvement of metabolic pathways and mitochondrial homeostasis in determining treatment response and their ability to provide promising classification signals with detection levels in both the colon and the bloodstream.
Authors
- Itziar Martín‐Ruiz (ORCID: https://orcid.org/0000-0002-9915-8101)
- Monika González-Lopez (ORCID: https://orcid.org/0000-0003-1506-0332)
- Ainize Peña‐Cearra (ORCID: https://orcid.org/0000-0003-3855-6664)
- Janire Castelo (ORCID: https://orcid.org/0000-0002-9628-8242)
- Azucena Salas (ORCID: https://orcid.org/0000-0003-4572-2907)
- Julián Panés (ORCID: https://orcid.org/0000-0002-4971-6902)
- A M Corraliza (ORCID: https://orcid.org/0000-0002-3067-7763)
- Laura Irwin (ORCID: https://orcid.org/0000-0001-5752-2764)
- M. Fuertes (ORCID: https://orcid.org/0000-0001-5454-0078)
- Leticia Abecia (ORCID: https://orcid.org/0000-0003-4097-8903)
- Héctor Rodrı́guez (ORCID: https://orcid.org/0000-0002-9948-2497)
- Iago Rodríguez–Lago (ORCID: https://orcid.org/0000-0003-1133-4578)
- Ana M. Aransay (ORCID: https://orcid.org/0000-0002-8271-612X)
- Juan Anguíta (ORCID: https://orcid.org/0000-0003-2061-7182)
- Urko M. Marigorta (ORCID: https://orcid.org/0000-0002-9087-6609)
- Dimitrios Kioroglou (ORCID: https://orcid.org/0000-0003-3495-4585)
- Jone Ortiz de Zárate
- Iratxe Seoane (ORCID: https://orcid.org/0009-0008-4284-1381)
Institutions
- Ikerbasque (ES)
- University of the Basque Country (ES)
- Instituto de Salud Carlos III (ES)
- BioCruces Health research Institute (ES)
- Euskadiko Parke Teknologikoa (ES)
- Hospital de Basurto (ES)
- CIC bioGUNE (ES)
- Hospital Clínic de Barcelona (ES)
- Hospital de Galdakao (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1093/ibd/izaf015
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Eusko Jaurlaritza
- Euskal Herriko Unibertsitatea
- Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona
- Agencia Estatal de Investigación