[Effects of electroacupuncture on mitochondrial autophagy and Sirt1/FOXO3/PINK1/Parkin pathway in rats with learning-memory impairment after cerebral ischemia reperfusion injury].

EA at "Shenting" (GV24) and "Baihui" (GV20) can relieve the symptoms of neurological deficits and improve the learning-memory ability in MCAO/R rats, its mechanism may relate to the modulation of Sirt1/FOXO3/PINK1/Parkin pathway and the enhancement of mitochondrial autophagy.

Authors

Kaiqi Su
Zhuan Lv
Xiaodong Feng (ORCID: https://orcid.org/0000-0003-2700-8304)
Lulu Chen (ORCID: https://orcid.org/0000-0001-9621-9231)
Hao Liu (ORCID: https://orcid.org/0000-0002-8687-3237)
Ming Zhang (ORCID: https://orcid.org/0000-0003-4343-2551)
Jing Gao (ORCID: https://orcid.org/0000-0002-2131-7301)

Institutions

Zhengzhou University (CN)
Henan University of Engineering (CN)
First Affiliated Hospital of Henan University of Traditional Chinese Medicine (CN)
First Affiliated Hospital of Henan University (CN)
First Affiliated Hospital of Zhengzhou University (CN)
Henan Agricultural University (CN)

Publication Details

Journal: PubMed
Published: 2025-02-12
DOI: https://doi.org/10.13703/j.0255-2930.20231012-k0005
Primary Topic: Acupuncture Treatment Research Studies
Type: article

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article

[Effects of electroacupuncture on mitochondrial autophagy and Sirt1/FOXO3/PINK1/Parkin pathway in rats with learning-memory impairment after cerebral ischemia reperfusion injury].

Kaiqi Su, Zhuan Lv, Xiaodong Feng, Lulu Chen et al.

Feb 12, 2025

PubMed

Acupuncture Treatment Research Studies

article

[Effects of electroacupuncture on mitochondrial autophagy and Sirt1/FOXO3/PINK1/Parkin pathway in rats with learning-memory impairment after cerebral ischemia reperfusion injury].

Kaiqi Su, Zhuan Lv, Xiaodong Feng, Lulu Chen, Hao Liu, Ming Zhang, Jing Gao

February 12, 2025article en

Abstract

EA at "Shenting" (GV24) and "Baihui" (GV20) can relieve the symptoms of neurological deficits and improve the learning-memory ability in MCAO/R rats, its mechanism may relate to the modulation of Sirt1/FOXO3/PINK1/Parkin pathway and the enhancement of mitochondrial autophagy.

PubMedVol. 45(2)

Zhengzhou University (CN), Henan University of Engineering (CN), First Affiliated Hospital of Henan University of Traditional Chinese Medicine (CN), First Affiliated Hospital of Henan University (CN), First Affiliated Hospital of Zhengzhou University (CN), Henan Agricultural University (CN)

Acupuncture Treatment Research Studies

DOI Source OpenAlex

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[Effects of electroacupuncture on mitochondrial autophagy and Sirt1/FOXO3/PINK1/Parkin pathway in rats with learning-memory impairment after cerebral ischemia reperfusion injury]. — Kaiqi Su, Zhuan Lv, et al. · PubMed (2025) | TGRS Research Map | TGRS