Prevalence of idiopathic normal pressure hydrocephalus in older adult population in Shanghai, China: A population‐based observational study

<sup>**</sup>Significant Prevalence<sup>**</sup>: The study identified a substantial prevalence of iNPH in older adults, with rates increasing significantly with age, particularly among those aged 90-99 years and centenarians. <sup>**</sup>Diagnostic Approach<sup>**</sup>: The research utilized novel diagnostic methodologies by integrating the DESH score or Radscale score with stringent clinical symptoms, providing a closer approximation to the true prevalence of iNPH. <sup>**</sup>Gender Disparity<sup>**</sup>: A marked gender difference was observed, with the prevalence of iNPH being significantly higher in males compared to females across all age groups. <sup>**</sup>Clinical Implications<sup>**</sup>: The findings underscore the importance of considering iNPH in the differential diagnosis of dementia, particularly among older male patients presenting with cognitive impairment and gait disturbances. <sup>**</sup>Public Health Impact<sup>**</sup>: The estimated number of s-probable iNPH patients in Shanghai highlights the need for increased awareness and better management strategies for this underdiagnosed condition in the aging population.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-02-01
DOI
https://doi.org/10.1002/alz.14525
Citations
1
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.91

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article

Prevalence of idiopathic normal pressure hydrocephalus in older adult population in Shanghai, China: A population‐based observational study

Yan Xing, Shihong Li, Xuhao Fang, Yao Deng et al.
1 citations
Alzheimer s & Dementia
Cerebrospinal fluid and hydrocephalus
0.91
article

Prevalence of idiopathic normal pressure hydrocephalus in older adult population in Shanghai, China: A population‐based observational study

Yan Xing, Shihong Li, Xuhao Fang, Yao Deng, Jin Hu, Chunyan Liu, Li Zhang, Feng Tang, Xinxin Xu, Renling Mao
article en
1 citations

Abstract

<sup>**</sup>Significant Prevalence<sup>**</sup>: The study identified a substantial prevalence of iNPH in older adults, with rates increasing significantly with age, particularly among those aged 90-99 years and centenarians. <sup>**</sup>Diagnostic Approach<sup>**</sup>: The research utilized novel diagnostic methodologies by integrating the DESH score or Radscale score with stringent clinical symptoms, providing a closer approximation to the true prevalence of iNPH. <sup>**</sup>Gender Disparity<sup>**</sup>: A marked gender difference was observed, with the prevalence of iNPH being significantly higher in males compared to females across all age groups. <sup>**</sup>Clinical Implications<sup>**</sup>: The findings underscore the importance of considering iNPH in the differential diagnosis of dementia, particularly among older male patients presenting with cognitive impairment and gait disturbances. <sup>**</sup>Public Health Impact<sup>**</sup>: The estimated number of s-probable iNPH patients in Shanghai highlights the need for increased awareness and better management strategies for this underdiagnosed condition in the aging population.

Alzheimer s & DementiaVol. 21(2)
Fudan University (CN), Huadong Hospital (CN), Huashan Hospital (CN), Aviation General Hospital (CN)
Shanghai Municipal Health Commission, National Natural Science Foundation of China, Natural Science Foundation of Beijing Municipality
Openalex Percentile: Top 31%
Cerebrospinal fluid and hydrocephalus
0.91
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