Dysphagia following transcatheter mitral valve-in-ring replacement complicated by neo-left ventricular outflow tract obstruction: a case report

To our knowledge, this is the first case report of TMVR complicated by reversible neo-LVOT obstruction with only trivial paravalvular regurgitation causing intravascular haemolysis and subsequent dysphagia. The management of dysphagia secondary to intravascular haemolysis due to neo-LVOT obstruction is challenging. This is because of the complex haemodynamic interplay between reduced oral intake, a high output state with anaemia, increased ventricular contractility, tachycardia, and worsening dynamic obstruction, all part of a vicious cycle (<i>Summary figure</i>).

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Journal
European Heart Journal - Case Reports
Published
2025-02-13
DOI
https://doi.org/10.1093/ehjcr/ytaf081
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Dysphagia following transcatheter mitral valve-in-ring replacement complicated by neo-left ventricular outflow tract obstruction: a case report

O. Raffel, K. Lau, Kim Greaves, Stephanie R. Sargent et al.
European Heart Journal - Case Reports
Cardiac Valve Diseases and Treatments
article

Dysphagia following transcatheter mitral valve-in-ring replacement complicated by neo-left ventricular outflow tract obstruction: a case report

O. Raffel, K. Lau, Kim Greaves, Stephanie R. Sargent, Eddy Xiong
article en

Abstract

To our knowledge, this is the first case report of TMVR complicated by reversible neo-LVOT obstruction with only trivial paravalvular regurgitation causing intravascular haemolysis and subsequent dysphagia. The management of dysphagia secondary to intravascular haemolysis due to neo-LVOT obstruction is challenging. This is because of the complex haemodynamic interplay between reduced oral intake, a high output state with anaemia, increased ventricular contractility, tachycardia, and worsening dynamic obstruction, all part of a vicious cycle (<i>Summary figure</i>).

European Heart Journal - Case ReportsVol. 9(4)
Griffith University (AU), Queensland University of Technology (AU), The University of Queensland (AU), Sunshine Coast University Hospital (AU), Prince Charles Hospital (AU)
Openalex Percentile: Top 95%
Cardiac Valve Diseases and Treatments
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Dysphagia following transcatheter mitral valve-in-ring replacement complicated by neo-left ventricular outflow tract obstruction: a case report — O. Raffel, K. Lau, et al. · European Heart Journal - Case Reports (2025) | TGRS Research Map | TGRS