Relationship of left piriform cortex network centrality with temporal lobe epilepsy duration and drug resistance
We demonstrated an increased centrality of the left PC in patients with drug-resistant TLE, which was also associated with the epilepsy duration. Recurring seizures over long periods may lead to changes of network properties of the PC. Large effects immediately rostral to our delineated PC region suggest a role of olfactory cortex anterior to the limen insulae in epileptogenic networks.
Authors
- André Kemmling (ORCID: https://orcid.org/0000-0001-8930-1894)
- Susanne Knake (ORCID: https://orcid.org/0000-0002-6298-0513)
- Louise Linka (ORCID: https://orcid.org/0000-0003-1711-7072)
- Alexander Grote (ORCID: https://orcid.org/0000-0002-6545-0622)
- Marcus Belke (ORCID: https://orcid.org/0000-0001-5131-1579)
- Felix Zahnert (ORCID: https://orcid.org/0000-0003-0366-6724)
- Katja Menzler (ORCID: https://orcid.org/0000-0001-8289-480X)
- Lars Timmermann (ORCID: https://orcid.org/0000-0002-5301-3580)
- Christopher Nimsky (ORCID: https://orcid.org/0000-0002-8216-9410)
- Paul Reichert
Institutions
- Goethe University Frankfurt (DE)
- Philipps University of Marburg (DE)
- Brain (Germany) (DE)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/ene.70018
- Citations
- 3
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.39
Funders
- Philipps-Universität Marburg
- Deutsche Gesellschaft für Epileptologie