Digital polymerase chain reaction quantification of hematopoietic chimerism by insertion/deletion: A personalized selection for different chimerism status

Our newly developed system demonstrates excellent repeatability and sensitivity, particularly in detecting. It is expected to show good applicability in Chinese transplant patients. Selecting between dPCR and STR testing based on individual chimerism status can facilitate sensitive and accurate analysis, enable timely therapeutic intervention, and support effective relapse monitoring in clinical practice.