Unveiling the Impact of Total Body Fluid Dynamics on Chronic Rhinosinusitis With Sinonasal Polyposis

Significantly elevated serum creatinine levels in patients with sinonasal polyposis may suggest a potential link with renal function or fluid regulation, warranting further research in larger cohorts to clarify this relationship. The regression model indicated a positive correlation between excess body water and the development of polyposis, with a weaker trend observed for other parameters. However, due to insufficient evidence, further research involving larger sample sizes across diverse geographic regions is recommended to validate their roles in the pathogenesis of sinonasal polyps.