Time in the therapeutic range, bleeding event, and their determinants in older patients with atrial fibrillation on warfarin in Ethiopia: multicenter cross-sectional study
This study highlights suboptimal warfarin therapy among older Ethiopian patients with AF. Poor anticoagulation was associated with advanced age, chronic kidney disease, and infrequent INR monitoring, while diabetes mellitus and high CHA₂DS₂-VASc scores increased bleeding risks. Close monitoring and frequent INR checks are essential to improving outcomes.
Authors
- Bereket Bahiru Tefera (ORCID: https://orcid.org/0000-0002-1758-348X)
- Desalegn Getnet Demsie (ORCID: https://orcid.org/0000-0001-9384-7398)
- Destaw Endeshaw (ORCID: https://orcid.org/0000-0001-9737-4604)
- Chernet Tafere
- Dessale Abate Beyene (ORCID: https://orcid.org/0000-0003-2491-6251)
- Malede Berihun
- Taklo Simeneh Yazie (ORCID: https://orcid.org/0000-0003-1218-5826)
Institutions
- Debre Berhan University (ET)
- Debre Tabor University (ET)
- Bahir Dar University (ET)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.3389/fphar.2025.1541592
- Citations
- 1
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.39