Integrative analysis of m7G methylation-associated genes prognostic signature with immunotherapy and identification of LARP1 as a key oncogene in head and neck squamous cell carcinoma
The m7GRG-based prognostic model developed in this study holds strong clinical potential for predicting prognosis and therapeutic responses in HNSCC. The identification of LARP1 and its related regulatory pathways offers new avenues for targeted therapy in HNSCC.
Authors
- Zhekun Zhu (ORCID: https://orcid.org/0000-0001-9088-5890)
- Panpan Xu (ORCID: https://orcid.org/0000-0001-7966-2389)
- Juanjuan Dong (ORCID: https://orcid.org/0000-0002-7757-0218)
- Haotian Qin (ORCID: https://orcid.org/0000-0001-8898-921X)
- Min Liu (ORCID: https://orcid.org/0000-0001-5143-0420)
- Juan Xu (ORCID: https://orcid.org/0000-0002-3709-4165)
- Chao Wang (ORCID: https://orcid.org/0009-0009-5719-3628)
- Zheng Zhang (ORCID: https://orcid.org/0000-0002-6954-8790)
- Yuting Huang (ORCID: https://orcid.org/0000-0002-9779-6492)
- Zhou You
Institutions
- Anhui Medical University (CN)
- Chaohu Hospital of Anhui Medical University (CN)
- Peking University Shenzhen Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1520070
- Citations
- 5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.03