Creation of an innovative diagnostic framework for hepatocellular carcinoma employing bioinformatics techniques focused on senescence-related and pyroptosis-related genes
This study systematically elucidated the functions of genes associated with senescence and pyroptosis in LIHC cells. The constructed prognostic risk model serves to guide the development of personalized treatment plans, enhance patient management via risk stratification, facilitate the identification of high-risk patients, intensify monitoring or implement proactive interventions, thereby providing a novel perspective for the diagnosis and treatment of LIHC.
Authors
- Baixue Liu
- Chunhui Liu (ORCID: https://orcid.org/0000-0002-4462-0602)
- Youguang Ao (ORCID: https://orcid.org/0009-0005-7947-3832)
- Fang Bai (ORCID: https://orcid.org/0000-0003-1468-5568)
- Qi Wang (ORCID: https://orcid.org/0000-0003-3645-5739)
- Zhi Zhou (ORCID: https://orcid.org/0000-0002-4858-5111)
- Juan Huang (ORCID: https://orcid.org/0000-0002-2331-944X)
Institutions
- Xian Yang Central Hospital (CN)
- Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.3389/fonc.2025.1485421
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Inner Mongolia Medical University
- Education Department of Inner Mongolia Autonomous Region