The human 18S rRNA m6A methyltransferase METTL5 promotes tumorigenesis via DEPDC1 in lung squamous cell carcinoma
Our results revealed that METTL5 enhances DEPDC1 translation to contribute to tumorigenesis and poor prognosis, providing a potential prognostic biomarker and therapeutic target for LUSC.
Authors
- Jianjun Fu (ORCID: https://orcid.org/0000-0001-9792-002X)
- Yan Yang (ORCID: https://orcid.org/0009-0006-7177-1111)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.3389/fonc.2025.1522157
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61