Comparative transcriptomics reveals different profiles between diflubenzuron‐resistant and ‐susceptible phenotypes of the mosquito <i>Culex pipiens</i>
Adaptation to insecticides can involve transcriptional changes in genes encoding for multiple defense mechanisms. Our results identified the over-expression of transcripts associated with detoxification and cuticle synthesis in DFB-resistant individuals of Cx. pipiens. Multiple mechanisms, beyond the known target-site mechanism, may therefore contribute to the DFB-resistant phenotype. Together these findings corroborate the complexity underpinning the resistant phenotypes and provide important information for the implementation of effective control strategies against mosquito vectors. © 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Authors
- Daniele Porretta (ORCID: https://orcid.org/0000-0003-0430-3183)
- Valentina Mastrantonio (ORCID: https://orcid.org/0000-0001-7701-4716)
- Vontas John
- Luis H. Franco (ORCID: https://orcid.org/0000-0002-8143-1384)
- U.S. Sandra
- Romeo Bellini (ORCID: https://orcid.org/0000-0001-9336-9111)
- Castrignanò Tiziana
- Lucchesi Valentina
Institutions
- Agricultural University of Athens (GR)
- Università degli Studi della Tuscia (IT)
- Centro Agricoltura Ambiente (Italy) (IT)
- Sapienza University of Rome (IT)
- Foundation for Research and Technology Hellas (GR)
Publication Details
- Journal
- Pest Management Science
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1002/ps.8710
- Primary Topic
- Insect symbiosis and bacterial influences
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission