Investigation of protective effects of olanzapine on impaired learning and memory using behavioral tests in a rat model of Alzheimer’s disease
Our findings suggest that OLZ can restore cognitive performance and alleviate anxiety-like behavior following Aβ injection. Thus, OLZ may have both preventive and therapeutic potential for AD and could be considered a viable pharmacological option.
Authors
- Ebrahim Abbasi Oshaghi (ORCID: https://orcid.org/0000-0002-3405-562X)
- Masome Rashno (ORCID: https://orcid.org/0000-0002-1290-3499)
- Parsa Amiri (ORCID: https://orcid.org/0000-0001-5332-7574)
- Masoumeh Kourosh‐Arami (ORCID: https://orcid.org/0000-0002-8579-3331)
- Zoleikha Golipoor (ORCID: https://orcid.org/0000-0001-9661-0636)
- Alireza Komaki (ORCID: https://orcid.org/0000-0003-3865-9583)
- Samaneh Safari (ORCID: https://orcid.org/0000-0001-7163-5589)
- Somayeh Komaki
- Fatemeh Ramezani‐Aliakbari (ORCID: https://orcid.org/0000-0002-9697-6264)
Institutions
- Hamedan University of Medical Sciences (IR)
- Guilan University of Medical Sciences (IR)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-02-13
- DOI
- https://doi.org/10.3389/fnagi.2025.1376074
- Citations
- 1
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Hamadan University of Medical Sciences