Elevated levels of IRF1 and CASP1 as pyroptosis-related biomarkers for intestinal epithelial cells in Crohn’s disease
Our findings identified <i>IRF1</i> and <i>CASP1</i> as critical pyroptosis-related biomarkers for IECs in CD, contributing to the understanding of pyroptosis in CD pathogenesis.
Authors
- Xiaoping Lv (ORCID: https://orcid.org/0000-0001-7144-9508)
- Xiaofang Xu (ORCID: https://orcid.org/0000-0001-7986-1740)
- Junhua Fan
- Ziqian Huang (ORCID: https://orcid.org/0009-0000-3829-0582)
- Xiaodan Lv (ORCID: https://orcid.org/0000-0003-1877-4285)
- Shiquan Li (ORCID: https://orcid.org/0000-0003-3744-2737)
- Ruizhi Zeng
- Bing Han (ORCID: https://orcid.org/0000-0001-7600-6693)
- Jianing Lin
- Zhixi Huang
- Guangfu Lin
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Tumor Hospital of Guangxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1551547
- Citations
- 2
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61