Base Mediated 7-exo-dig Intramolecular Cyclization of Betti-propargyl Precursors: An Efficient Approach to 1,4-oxazepine Derivatives

This efficient and straightforward protocol proceeds under mild, metal-free conditions and has been shown to be applicable to a broad range of aldehydes and 2- aminopyridines.

Authors

Rozita Yazzaf
Mohammad Mahdavi (ORCID: https://orcid.org/0000-0002-4171-7310)
Mina Asadi

Institutions

University of Tehran (IR)
Tehran University of Medical Sciences (IR)

Publication Details

Journal: Current Organic Synthesis
Published: 2025-02-13
DOI: https://doi.org/10.2174/0115701794353226241209175136
Primary Topic: Synthesis and Biological Activity
Type: article
Field-Weighted Citation Impact: 0.00

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article

Base Mediated 7-exo-dig Intramolecular Cyclization of Betti-propargyl Precursors: An Efficient Approach to 1,4-oxazepine Derivatives

Rozita Yazzaf, Mohammad Mahdavi, Mina Asadi

Feb 13, 2025

Current Organic Synthesis

Synthesis and Biological Activity

article

Base Mediated 7-exo-dig Intramolecular Cyclization of Betti-propargyl Precursors: An Efficient Approach to 1,4-oxazepine Derivatives

Rozita Yazzaf, Mohammad Mahdavi, Mina Asadi

February 13, 2025article en

Abstract

This efficient and straightforward protocol proceeds under mild, metal-free conditions and has been shown to be applicable to a broad range of aldehydes and 2- aminopyridines.

Current Organic SynthesisVol. 22(6)

University of Tehran (IR), Tehran University of Medical Sciences (IR)

Good health and well-being

Openalex Percentile: Top 97%

Synthesis and Biological Activity

DOI Source OpenAlex

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Base Mediated 7-exo-dig Intramolecular Cyclization of Betti-propargyl Precursors: An Efficient Approach to 1,4-oxazepine Derivatives — Rozita Yazzaf, Mohammad Mahdavi, et al. · Current Organic Synthesis (2025) | TGRS Research Map | TGRS