Proteomics of stress-induced cardiomyopathy: insights from differential expression, protein interaction networks, and functional pathway enrichment in an isoproterenol-induced TTC mouse model

This study employed high-throughput liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify key proteins associated with energy metabolism, oxidative stress, inflammation, and cell death in TTC. These findings provide new insights into the molecular mechanisms of stress-induced myocardial injury and may offer potential therapeutic targets for mitigating cardiovascular damage under stress conditions.