<i>DNMT1</i> promotes the proliferation and migration of gastric cancer cells by inducing microRNA-125a-5p methylation to promote SERPINE1 protein
Our study revealed that <i>DNMT1</i> promoted SERPINE1 protein expression by inducing miR-125a-5p methylation, which led to the proliferation, migration and occurrence of EMT in GC cells.
Authors
- X.X. He (ORCID: https://orcid.org/0000-0002-1088-4845)
- Hui Wang (ORCID: https://orcid.org/0000-0001-7628-3519)
- Aoran Guan
- Hui Xie (ORCID: https://orcid.org/0000-0002-8526-2637)
- Yuewen Zhang (ORCID: https://orcid.org/0000-0003-1864-769X)
- Xi-Rui Fan
- Ruhong Li (ORCID: https://orcid.org/0009-0001-1864-7078)
Institutions
- Kunming Medical University (CN)
- Yan'an Hospital Affiliated To Kunming Medical University (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.4251/wjgo.v17.i3.98703
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00