Arginine Methylation by PRMT1 Affects ADAMTS13 Secretion and Enzymatic Activity
These results demonstrate the crucial role of arginine methylation in ADAMTS13 secretion and function. Our findings may shed new light on the mechanism of allosteric regulation of ADAMTS13, which may have a therapeutic implication.
Authors
- Karen Vanhoorelbeke (ORCID: https://orcid.org/0000-0003-2288-8277)
- Joshua Muia (ORCID: https://orcid.org/0000-0001-5011-2420)
- Zhijian Wu (ORCID: https://orcid.org/0000-0002-7189-3358)
- X. Long Zheng (ORCID: https://orcid.org/0000-0003-1680-5295)
- Liang Zheng (ORCID: https://orcid.org/0000-0003-0120-9343)
- Xinyang Zhao (ORCID: https://orcid.org/0000-0001-6677-7072)
- Jun Qu (ORCID: https://orcid.org/0000-0002-1346-6809)
- Szumam Liu (ORCID: https://orcid.org/0000-0003-2643-5048)
- Quintijn Bonnez (ORCID: https://orcid.org/0000-0001-7209-530X)
- Min Ma (ORCID: https://orcid.org/0000-0002-4203-5215)
Institutions
- Zunyi Medical University (CN)
- Research Institute for Chromatography (BE)
- Versiti Blood Center of Wisconsin (US)
- Institute of Reproductive Medicine (IN)
- Thrombosis Research Institute (GB)
- University at Buffalo, State University of New York (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1161/atvbaha.124.322249
- Citations
- 3
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.42