Restoring Vascular Smooth Muscle Cell Mitochondrial Function Attenuates Abdominal Aortic Aneurysm in Mice
VSMC mitochondrial damage is a pivotal factor in the development of AAA. The utilization of sHDL nanoparticles represents a promising novel therapeutic approach for AAA, aimed at restoring VSMC mitochondrial function.
Authors
- Anna Schwendeman (ORCID: https://orcid.org/0000-0002-8023-8080)
- Y. Eugene Chen (ORCID: https://orcid.org/0000-0003-2357-7825)
- Kristen Hong (ORCID: https://orcid.org/0000-0003-2742-4658)
- Guizhen Zhao (ORCID: https://orcid.org/0000-0002-2648-8986)
- Yaozhong Liu (ORCID: https://orcid.org/0000-0003-1994-2025)
- Wenjuan Mu (ORCID: https://orcid.org/0000-0003-0166-2789)
- Xiaokang Wu (ORCID: https://orcid.org/0000-0003-1020-6232)
- Yongjie Deng
- Hong Yu Liu (ORCID: https://orcid.org/0000-0003-1754-0145)
- Huilun Wang (ORCID: https://orcid.org/0000-0002-0583-1386)
- Haocheng Lu (ORCID: https://orcid.org/0000-0002-5740-8010)
- Lin Chang (ORCID: https://orcid.org/0000-0002-5621-8426)
- Yanhong Guo (ORCID: https://orcid.org/0000-0002-3334-9159)
- Yonghong Luo (ORCID: https://orcid.org/0000-0001-8996-9253)
- Minzhi Yu (ORCID: https://orcid.org/0000-0002-3141-7285)
- Yang Zhao (ORCID: https://orcid.org/0000-0002-1428-5145)
- Zhenguo Wang (ORCID: https://orcid.org/0000-0002-3158-2002)
- Jifeng Zhang (ORCID: https://orcid.org/0000-0001-5161-4705)
- Ying Zhao (ORCID: https://orcid.org/0000-0003-1839-8849)
- Yalun Cheng
Institutions
- Central South University (CN)
- University of Michigan (US)
- Southern University of Science and Technology (CN)
- World Wide Web Consortium (US)
- Michigan Center for Translational Pathology (US)
- Second Xiangya Hospital of Central South University (CN)
- University of Virginia (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1161/atvbaha.124.321730
- Citations
- 11
- Primary Topic
- Aortic aneurysm repair treatments
- Type
- article
- Field-Weighted Citation Impact
- 15.18