Restoring Vascular Smooth Muscle Cell Mitochondrial Function Attenuates Abdominal Aortic Aneurysm in Mice

VSMC mitochondrial damage is a pivotal factor in the development of AAA. The utilization of sHDL nanoparticles represents a promising novel therapeutic approach for AAA, aimed at restoring VSMC mitochondrial function.

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Publication Details

Journal
Arteriosclerosis Thrombosis and Vascular Biology
Published
2025-02-13
DOI
https://doi.org/10.1161/atvbaha.124.321730
Citations
11
Primary Topic
Aortic aneurysm repair treatments
Type
article
Field-Weighted Citation Impact
15.18
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article

Restoring Vascular Smooth Muscle Cell Mitochondrial Function Attenuates Abdominal Aortic Aneurysm in Mice

Anna Schwendeman, Y. Eugene Chen, Kristen Hong, Guizhen Zhao et al.
11 citations
Arteriosclerosis Thrombosis and Vascular Biology
Aortic aneurysm repair treatments
15.18
article

Restoring Vascular Smooth Muscle Cell Mitochondrial Function Attenuates Abdominal Aortic Aneurysm in Mice

Anna Schwendeman, Y. Eugene Chen, Kristen Hong, Guizhen Zhao, Yaozhong Liu, Wenjuan Mu, Xiaokang Wu, Yongjie Deng, Hong Yu Liu, Huilun Wang, Haocheng Lu, Lin Chang, Yanhong Guo, Yonghong Luo, Minzhi Yu, Yang Zhao, Zhenguo Wang, Jifeng Zhang, Ying Zhao, Yalun Cheng
article en
11 citations

Abstract

VSMC mitochondrial damage is a pivotal factor in the development of AAA. The utilization of sHDL nanoparticles represents a promising novel therapeutic approach for AAA, aimed at restoring VSMC mitochondrial function.

Arteriosclerosis Thrombosis and Vascular BiologyVol. 45(4)
Central South University (CN), University of Michigan (US), Southern University of Science and Technology (CN), World Wide Web Consortium (US), Michigan Center for Translational Pathology (US), Second Xiangya Hospital of Central South University (CN), University of Virginia (US)
Good health and well-being
Openalex Percentile: Top 1%
Aortic aneurysm repair treatments
15.18
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