German Asthma Net: Characterisation of responders to anti-IL-5 and anti-IL-5(R) therapy
These results underscore that long-term anti-IL-5/IL-5(R) therapy reduces exacerbation and corticosteroid burden, especially in patients with severe disease and high type 2 inflammatory burden. Contrastingly, low baseline corticosteroid use and markers of good asthma control predicted remission and super-responder status.
Authors
- Margret Jandl (ORCID: https://orcid.org/0000-0001-5964-0211)
- Andreas Renner (ORCID: https://orcid.org/0000-0002-1414-5433)
- Slagjana Stoshikj (ORCID: https://orcid.org/0009-0000-4418-0734)
- Katrin Milger (ORCID: https://orcid.org/0000-0003-2914-8773)
- Roland Buhl (ORCID: https://orcid.org/0009-0001-5695-5899)
- Christian Taube (ORCID: https://orcid.org/0000-0002-3546-1398)
- Stephanie Korn (ORCID: https://orcid.org/0009-0001-2239-5029)
- Sonja Zehetmayer (ORCID: https://orcid.org/0000-0001-6863-7997)
- Christina Bal (ORCID: https://orcid.org/0000-0003-3591-9490)
- Eckard Hamelmann (ORCID: https://orcid.org/0000-0002-2996-8248)
- Olaf Schmidt (ORCID: https://orcid.org/0000-0003-0098-7960)
- Marco Idzko
- Dirk Skowasch (ORCID: https://orcid.org/0000-0003-2377-5936)
- Christian Schulz (ORCID: https://orcid.org/0000-0002-4861-4517)
- Rainer Ehmann
Institutions
- Johannes Gutenberg University Mainz (DE)
- Bielefeld University (DE)
- University Hospital Bonn (DE)
- University Hospital Regensburg (DE)
- Ruhrlandklinik (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Evangelisches Krankenhaus Bielefeld (DE)
- German Center for Lung Research (DE)
- Praxis für Humangenetik (DE)
- Hamburg Institute for Therapy Research (DE)
- Medical University of Vienna (AT)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Pulmonology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1080/25310429.2025.2460868
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.16