Exploring the causal associations of the gut microbiota and plasma metabolites with ovarian cancer: an approach of mendelian randomization analysis combined with network pharmacology and molecular docking
Our MR analysis demonstrated that the gut microbiota and metabolites are causally associated with OC, which has significant potential for the early detection and diagnosis of OC and EOC subtypes, providing valuable insights into this area of research.
Authors
- Chenhuan Ding (ORCID: https://orcid.org/0000-0003-2534-8946)
- Chen Wang (ORCID: https://orcid.org/0000-0001-7857-5435)
- Junfeng Guo
- He Li (ORCID: https://orcid.org/0000-0002-8617-6503)
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1186/s13048-025-01610-9
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- National Natural Science Foundation of China