Abnormal Elevation of the Expression of Costimulatory Molecule CD226 in Graves' Disease: Two Cross-Sectional Studies

This study demonstrates for the first time the elevated expression of CD226 in CD4+ T cells and thyroid tissue of NOGD. The abnormal elevation of CD226 is correlated with clinical indicators. It suggests that the co-stimulatory molecule CD226 is involved in the pathogenesis of GD.

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Journal
Endocrine Metabolic & Immune Disorders - Drug Targets
Published
2025-02-12
DOI
https://doi.org/10.2174/0118715303337480250107052116
Primary Topic
Cardiac Fibrosis and Remodeling
Type
article
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article

Abnormal Elevation of the Expression of Costimulatory Molecule CD226 in Graves' Disease: Two Cross-Sectional Studies

Yuqing Wu, Tiantian Cai, Zhaowei Huang, Yanfei Jiang et al.
Endocrine Metabolic & Immune Disorders - Drug Targets
Cardiac Fibrosis and Remodeling
article

Abnormal Elevation of the Expression of Costimulatory Molecule CD226 in Graves' Disease: Two Cross-Sectional Studies

Yuqing Wu, Tiantian Cai, Zhaowei Huang, Yanfei Jiang, Xinwei Zhang, Jin‐an Zhang, Xuerong Liu, Rong-hua Song
article en

Abstract

This study demonstrates for the first time the elevated expression of CD226 in CD4+ T cells and thyroid tissue of NOGD. The abnormal elevation of CD226 is correlated with clinical indicators. It suggests that the co-stimulatory molecule CD226 is involved in the pathogenesis of GD.

Endocrine Metabolic & Immune Disorders - Drug TargetsVol. 25
Shanghai University of Traditional Chinese Medicine (CN), Yan'an University (CN), Shanghai University of Medicine and Health Sciences (CN)
Good health and well-being
Openalex Percentile: Top 95%
Cardiac Fibrosis and Remodeling
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