Mitigation of Radiation-induced Acute Hematopoietic System and Intestine Injury by Resveratrol-loaded Polymeric Nanoparticles after Whole Body Irradiation in Mice
The findings suggest that resveratrol-loaded polymeric-based nanocapsules can be an effective approach to mitigate radiation-induced damage to the hematopoietic system and intestine after whole-body exposure to X-ray radiation in mice. Further research is needed to explore the optimal dose and timing of resveratrol administration and to investigate the potential for clinical translation of this approach.
Authors
- Elham Arkan (ORCID: https://orcid.org/0000-0001-5518-2145)
- Faranak Aghaz (ORCID: https://orcid.org/0000-0002-7311-4071)
- Amir Kiani (ORCID: https://orcid.org/0000-0002-7802-2117)
- Masoud Najaf Najafi (ORCID: https://orcid.org/0000-0002-0188-6910)
- Khodabakhsh Rashidi (ORCID: https://orcid.org/0000-0002-8144-074X)
- Mohammad Mohammadi (ORCID: https://orcid.org/0000-0003-1303-6574)
Institutions
- Kermanshah University of Medical Sciences (IR)
Publication Details
- Journal
- Current Radiopharmaceuticals
- Published
- 2025-02-13
- DOI
- https://doi.org/10.2174/0118744710335266250206060602
- Citations
- 2
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 2.72