Participant Sex Ratio and Race Reporting in the Clinical Trials for the Management and Outcomes of Deep Venous Thrombosis

Our study aims to compare the outcomes of repair of portal vein vs ligation.Methods: We performed a 6-year (2016-2022) analysis of the Nationwide Trauma Data Bank pertaining to the United States.This study includes all patients with portal vein injury by International Classification of Diseases, Tenth Revision diagnosis codes.The primary outcome measure was in-hospital mortality.The secondary outcome measure was inhospital complications.In-hospital complications were length of stay, intensive care unit (ICU) length of stay, and surgical site infection.To compare the two surgical treatments, we analyzed categorical variables by the c2 test and numerical variables by the Wilcoxon rank sum test.To compare the outcomes, we performed propensity score matching between the two treatment groups.We controlled demographic info (age, gender, race, hospital property, etc), trauma type, mechanism, and severities of injury.Results: A total of 875 patients with portal vein injury were extracted, of whom 361 underwent surgical treatment.With further analysis, we found 275 patients (76.2%) underwent repair vs 86 (23.8%) ligation of portal vein.The age, BMI, sex, race, Glasgow Coma Scale, trauma type, mechanism of injury and hospital type were similar between both groups with no statistically significant differences (Table ).We observed a higher median of the Injury Severity Score (ISS) among ligation patients (33; IQR, 25-41).Hospital mortality, length of stay, and ICU length of stay were not statistically different between both groups.After matching the two cohorts, the hospital mortality and length of stay show non-significant differences.Conclusions: Our study highlights there was no significant difference between repair and ligation for portal vein injury patients.These findings suggest that ligation of portal could be a suitable alternative for repair surgery.

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Publication Details

Journal
Journal of Vascular Surgery Venous and Lymphatic Disorders
Published
2025-02-13
DOI
https://doi.org/10.1016/j.jvsv.2024.102111
Primary Topic
Sex and Gender in Healthcare
Type
article
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article

Participant Sex Ratio and Race Reporting in the Clinical Trials for the Management and Outcomes of Deep Venous Thrombosis

Faisal Aziz, Ahsan Zil‐E‐Ali, Aditya Safaya, Kristine L. So et al.
1 links
Journal of Vascular Surgery Venous and Lymphatic Disorders
Sex and Gender in Healthcare
article

Participant Sex Ratio and Race Reporting in the Clinical Trials for the Management and Outcomes of Deep Venous Thrombosis

Faisal Aziz, Ahsan Zil‐E‐Ali, Aditya Safaya, Kristine L. So, A. Ari Hakimi, Alpha Tall
article en

Abstract

Our study aims to compare the outcomes of repair of portal vein vs ligation.Methods: We performed a 6-year (2016-2022) analysis of the Nationwide Trauma Data Bank pertaining to the United States.This study includes all patients with portal vein injury by International Classification of Diseases, Tenth Revision diagnosis codes.The primary outcome measure was in-hospital mortality.The secondary outcome measure was inhospital complications.In-hospital complications were length of stay, intensive care unit (ICU) length of stay, and surgical site infection.To compare the two surgical treatments, we analyzed categorical variables by the c2 test and numerical variables by the Wilcoxon rank sum test.To compare the outcomes, we performed propensity score matching between the two treatment groups.We controlled demographic info (age, gender, race, hospital property, etc), trauma type, mechanism, and severities of injury.Results: A total of 875 patients with portal vein injury were extracted, of whom 361 underwent surgical treatment.With further analysis, we found 275 patients (76.2%) underwent repair vs 86 (23.8%) ligation of portal vein.The age, BMI, sex, race, Glasgow Coma Scale, trauma type, mechanism of injury and hospital type were similar between both groups with no statistically significant differences (Table ).We observed a higher median of the Injury Severity Score (ISS) among ligation patients (33; IQR, 25-41).Hospital mortality, length of stay, and ICU length of stay were not statistically different between both groups.After matching the two cohorts, the hospital mortality and length of stay show non-significant differences.Conclusions: Our study highlights there was no significant difference between repair and ligation for portal vein injury patients.These findings suggest that ligation of portal could be a suitable alternative for repair surgery.

Journal of Vascular Surgery Venous and Lymphatic DisordersVol. 13(2)
Pennsylvania State University (US), Penn State Milton S. Hershey Medical Center (US)
Gender equality
Openalex Percentile: Top 96%
Sex and Gender in Healthcare
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