First‐In‐Human Dose Finding Study of Venadaparib (<scp>IDX</scp>‐1197), a Potent and Selective <scp>PARP</scp> Inhibitor, in Patients With Advanced Solid Tumors

Further studies are warranted to explore efficacy and safety of venadaparib in other tumor types and in combination with various agents, as well as to explore relevant biomarkers. (ClinicalTrials.gov ID: NCT03317743).

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Publication Details

Journal
Cancer Medicine
Published
2025-02-01
DOI
https://doi.org/10.1002/cam4.70576
Citations
2
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
2.09
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article

First‐In‐Human Dose Finding Study of Venadaparib (IDX‐1197), a Potent and Selective PARP Inhibitor, in Patients With Advanced Solid Tumors

Myongjae Lee, Kyun‐Seop Bae, Eun‐Jihn Roh, Jeongsook Bang et al.
2 citations
Cancer Medicine
PARP inhibition in cancer therapy
2.09
article

First‐In‐Human Dose Finding Study of Venadaparib (IDX‐1197), a Potent and Selective PARP Inhibitor, in Patients With Advanced Solid Tumors

Myongjae Lee, Kyun‐Seop Bae, Eun‐Jihn Roh, Jeongsook Bang, Sung‐Bae Kim, Kyoung Soo Ha, Chan‐Young Ock, Jong‐Ha Lim, Jae‐Lyun Lee, Won Sik Lee, Yong‐Man Kim, Min Hong
article en
2 citations

Abstract

Further studies are warranted to explore efficacy and safety of venadaparib in other tumor types and in combination with various agents, as well as to explore relevant biomarkers. (ClinicalTrials.gov ID: NCT03317743).

Cancer MedicineVol. 14(4)
Ulsan College (KR), Asan Medical Center (KR), University of Ulsan (KR), Ildong (South Korea) (KR)
Good health and well-being
Openalex Percentile: Top 14%
PARP inhibition in cancer therapy
2.09
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