Using individual barcodes to increase quantification power of massively parallel reporter assays
With BCalm, we provide a new tool for analyzing MPRA data which is robust and accurate on real MPRA datasets. The package is available at https://github.com/kircherlab/BCalm .
Authors
- Pia Keukeleire (ORCID: https://orcid.org/0000-0002-8828-636X)
- Max Schubach (ORCID: https://orcid.org/0000-0002-2032-6679)
- Jonathan D. Rosen (ORCID: https://orcid.org/0000-0001-6396-4219)
- Martin Kircher (ORCID: https://orcid.org/0000-0001-9278-5471)
- Angelina Göbel-Knapp
- Kilian Salomon (ORCID: https://orcid.org/0009-0009-3182-7987)
Institutions
- University of North Carolina at Chapel Hill (US)
- University Hospital Schleswig-Holstein (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- BMC Bioinformatics
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1186/s12859-025-06065-9
- Citations
- 6
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- Universität zu Lübeck
- Berlin Institute of Health