Overexpression and oncogenic role of RIPK3 in acute myeloid leukemia associated with specific subtypes and treatment outcome
Overexpression of RIPK3 was associated with specific subtypes of AML, such as FAB-M4/M5, normal karyotype and NPM1 mutation, and may facilitate the leukemic development. Moreover, RIPK3 overexpression was associated poor prognosis, and may guide treatment choice in AML.
Authors
- Ting‐juan Zhang (ORCID: https://orcid.org/0000-0003-1533-0646)
- Jing‐dong Zhou (ORCID: https://orcid.org/0000-0003-1476-926X)
- Liu-chao Zhang
- Zi‐jun Xu (ORCID: https://orcid.org/0000-0002-5051-6799)
- Yangjing Zhao (ORCID: https://orcid.org/0000-0002-6706-782X)
- Ming‐qiang Chu
- Yun Wang (ORCID: https://orcid.org/0000-0001-6521-0445)
- Jiang Lin (ORCID: https://orcid.org/0000-0002-4704-9157)
- Jun Qian (ORCID: https://orcid.org/0000-0002-6429-2933)
Institutions
- Jiangsu University (CN)
- Affiliated Hospital of Jiangsu University (CN)
- Qidong Liver Cancer Prevention Research (CN)
- Zhanjiang Experimental Station (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1186/s12885-025-13613-2
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province