Exposure to gonadotropin-releasing hormone agonist in early pregnancy leads to adverse pregnancy outcomes: a retrospective analysis
Exposure to GnRH-a during the luteal phase of down-regulation can adversely affect pregnancy outcomes. Therefore, we recommend contraception during the IVF/ICSI down-regulation. A higher dose of progesterone during early pregnancy is needed for infertile women who conceive spontaneously after exposure to GnRH-a.
Authors
- D Zhang
- Jinyu Lu
- Ruochun Wu
- B W Li
- Mimi Xiong
- Wenjun Wang
- Nan Dong (ORCID: https://orcid.org/0000-0002-6419-5463)
Institutions
- Sun Yat-sen University (CN)
- Hainan Maternal and Child Health Hospital (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Guangdong Provincial People's Hospital (CN)
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1007/s00404-024-07914-3
- Citations
- 2
- Primary Topic
- Assisted Reproductive Technology and Twin Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- Natural Science Foundation of Guangdong Province