Modern tools for the functionalization of C(sp3) centers by catalysis

In the quest for molecular complexity, the direct and selective functionalization of C(sp 3 ) centers is of paramount importance. As sulfur- and/or fluorine-containing molecules are particularly important, the development of methods to (regio)selectively introduce moieties containing these atoms on a C(sp 3 ) center by direct C–H bond functionalization or decarboxylative reaction has garnered our interest in the last few years. Given the challenges that the direct functionalization of C(sp 3 ) centers represents, this account summarizes our recent contributions thanks to strategies based on transition metal catalysis and photochemistry.