Do trial benefits predict real-world gains in metastatic castration resistant prostate cancer

After adjusting for treatment selection bias, RCT OS and RCT rPFS estimates serve as useful, or even conservative, predictors of RW OS gains.

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Publication Details

Journal
JNCI Cancer Spectrum
Published
2025-02-13
DOI
https://doi.org/10.1093/jncics/pkaf018
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Do trial benefits predict real-world gains in metastatic castration resistant prostate cancer

Bhakti Arondekar, Alexander Niyazov, Stephen J. Freedland, Neal Masia et al.
JNCI Cancer Spectrum
Prostate Cancer Treatment and Research
article

Do trial benefits predict real-world gains in metastatic castration resistant prostate cancer

Bhakti Arondekar, Alexander Niyazov, Stephen J. Freedland, Neal Masia, Darius Lakdawalla, Sarah Axeen, Alice Chen
article en

Abstract

After adjusting for treatment selection bias, RCT OS and RCT rPFS estimates serve as useful, or even conservative, predictors of RW OS gains.

JNCI Cancer SpectrumVol. 9(2)
University of Southern California (US), Cedars-Sinai Medical Center (US), Pfizer (United States) (US), Columbia University (US)
Pfizer
Good health and well-being
Openalex Percentile: Top 96%
Prostate Cancer Treatment and Research
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