The fractionation effect on proton RBE in a late normal tissue damage model in vivo
The findings demonstrate that fractionated doses enhance the RBE for a late damage endpoint and lead to an earlier onset of severe late effects than its photon counterpart in vivo.
Authors
- Harald Spejlborg (ORCID: https://orcid.org/0000-0002-9530-9451)
- Fardous Reaz (ORCID: https://orcid.org/0009-0002-8332-9655)
- Cathrine Bang Overgaard
- Niels Bassler (ORCID: https://orcid.org/0000-0002-4160-1078)
- Brita Singers Sørensen (ORCID: https://orcid.org/0000-0002-3955-4735)
- Cai Grau (ORCID: https://orcid.org/0000-0003-3548-3527)
- P.R. Poulsen (ORCID: https://orcid.org/0000-0001-9940-7609)
- Jens Overgaard (ORCID: https://orcid.org/0000-0002-0814-8179)
Institutions
- Aarhus University Hospital (DK)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1016/j.radonc.2025.110792
- Citations
- 1
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Kræftens Bekæmpelse
- Helga og Peter Kornings Fond
- Novo Nordisk Fonden
- Fonden til Lægevidenskabens Fremme