A retrospective analysis of placental histopathological findings in gestational diabetes mellitus (GDM)
Our study highlights MVM lesions as a prominent feature in the placentas of GDM pregnancies, especially when associated with FGR. These lesions are linked to adverse perinatal outcomes, emphasizing the need for enhanced antenatal care in these cases. The study contributes insights into the complex relationship between GDM, placental pathology and adverse fetal outcomes, laying the foundation for future investigations into early interventional strategies.
Authors
- Joseph M. Byrne
- Niccole Ranaei‐Zamani (ORCID: https://orcid.org/0000-0001-8654-9253)
- J. Ciaran Hutchinson (ORCID: https://orcid.org/0000-0002-1708-2634)
- Sara Hillman (ORCID: https://orcid.org/0000-0003-2971-6865)
Institutions
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- Institute for Reproductive Health (US)
- University College London (GB)
Publication Details
- Journal
- Placenta
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1016/j.placenta.2025.02.008
- Citations
- 8
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 16.46