High Levels of C5a Are Associated With Reduced Macular Sensitivity in Patients With Myeloproliferative Neoplasms
We found that high levels of the systemic inflammation marker C5a are associated with reduced macular sensitivity, regardless of the presence of visible degenerative changes in the macular area. These findings suggest an early contribution of the complement system to macular sensitivity.
Authors
- Marie Krogh Nielsen (ORCID: https://orcid.org/0000-0003-3804-7296)
- Torben Lykke Sørensen (ORCID: https://orcid.org/0000-0002-6790-0199)
- Kathrine Gotfredsen (ORCID: https://orcid.org/0000-0001-7392-9871)
- Charlotte Liisborg (ORCID: https://orcid.org/0000-0002-6353-6027)
- Lasse Kjær (ORCID: https://orcid.org/0000-0001-6767-0226)
- Hans Carl Hasselbalch (ORCID: https://orcid.org/0000-0003-3936-8032)
- Morten Kranker Larsen (ORCID: https://orcid.org/0000-0002-2873-5928)
- Vibe Skov (ORCID: https://orcid.org/0000-0003-0097-7826)
- Andreas Abou-Taha
Institutions
- Odense University Hospital (DK)
- Zealand University Hospital (DK)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-02-13
- DOI
- https://doi.org/10.1167/iovs.66.2.41
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Synoptik-Fonden
- Lægeforeningen
- Region Sjælland