TRIM63 and Atrogin-1 are key drivers of systemic and muscle inflammation in patients with idiopathic inflammatory myopathies
TRIM63 and Atrogin-1 are expressed in PBMC and muscle from patients with IIM and correlate with serum cytokines, and chemokines. This mechanism may contribute to the inflammation-induced muscle atrophy in IIM.
Authors
- Guillermo Juárez‐Vega (ORCID: https://orcid.org/0000-0002-0633-0567)
- Brenda Marquina‐Castillo (ORCID: https://orcid.org/0000-0002-3825-1820)
- Nancy R. Mejía‐Domínguez (ORCID: https://orcid.org/0000-0002-5788-4586)
- Miguel Tapia‐Rodríguez (ORCID: https://orcid.org/0000-0002-2248-6596)
- Diana Gómez‐Martín (ORCID: https://orcid.org/0000-0002-1807-0045)
- Carlos A. Núñez‐Álvarez (ORCID: https://orcid.org/0000-0002-5051-0389)
- Javier Ríos-Valencia (ORCID: https://orcid.org/0000-0002-7965-5872)
- Abdiel Absalón‐Aguilar (ORCID: https://orcid.org/0000-0003-3967-8516)
- Fabiola Cassiano-Quezada
- Alfredo Pérez‐Fragoso (ORCID: https://orcid.org/0000-0003-2978-4200)
- Jiram Torres‐Ruiz (ORCID: https://orcid.org/0000-0002-7882-1488)
Institutions
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Clinical and Experimental Rheumatology
- Published
- 2024-09-09
- DOI
- https://doi.org/10.55563/clinexprheumatol/p2lma6
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Secretaría de Educación Pública