DOT1L Regulates Cellular Senescence during the Progression from Acute Kidney Injury to Chronic Kidney Disease via the microRNA-222-5p/WNT9B Signaling Pathway
DOT1L regulates cellular senescence through the miR-222-5p/WNT9B pathway in AKI. These findings suggest that DOT1L may serve as a potential therapeutic target to mitigate the progression of AKI to chronic kidney disease.
Authors
- Songtao Shou (ORCID: https://orcid.org/0000-0002-9959-3963)
- Qi Lv (ORCID: https://orcid.org/0000-0001-9076-7042)
- Heng Wu (ORCID: https://orcid.org/0000-0003-1870-5036)
- Guoyu Wu (ORCID: https://orcid.org/0000-0002-4906-0659)
- Heng Jin (ORCID: https://orcid.org/0000-0001-9264-1187)
- Yushanjiang Abudureheman
- Zhiyuan Liu (ORCID: https://orcid.org/0000-0001-7624-283X)
- Wei Wei (ORCID: https://orcid.org/0000-0002-4195-8325)
- Keke Sun (ORCID: https://orcid.org/0009-0009-2534-3265)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-0035-543X)
- Congcong Yao (ORCID: https://orcid.org/0009-0005-4911-7730)
- Ayinuer Paredong
Institutions
- Tianjin University (CN)
- Shanghai Jiao Tong University (CN)
- Tianjin Medical University General Hospital (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Fifth Tianjin Central Hospital (CN)
- Shanghai First People's Hospital (CN)
- Tianjin Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- American Journal of Nephrology
- Published
- 2025-02-12
- DOI
- https://doi.org/10.1159/000544694
- Citations
- 1
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.67