Single-Tube Multiplex PCR-SSP for the Detection of RHD Variant Alleles Commonly Found in Serologically D− Phenotype Individuals in a Thai Population

This study successfully established a simple and reliable molecular diagnostic platform for analyzing <i>RHD</i> variant alleles commonly found in serologically D- phenotype individuals in a Thai population. This technique could enable broader <i>RHD*01EL.01</i> (Asian-type DEL) analyses in high-prevalence areas such as Thailand and other countries in East and Southeast Asia, serving as an example for blood bank routine settings.

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Institutions

Publication Details

Journal
Transfusion Medicine and Hemotherapy
Published
2025-02-12
DOI
https://doi.org/10.1159/000544107
Citations
1
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
1.77

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article

Single-Tube Multiplex PCR-SSP for the Detection of RHD Variant Alleles Commonly Found in Serologically D− Phenotype Individuals in a Thai Population

Amornrat Romphruk, Chanvit Leelayuwat, Piyapong Simtong, Ornuma Pittayabumrung
1 citations
Transfusion Medicine and Hemotherapy
Blood groups and transfusion
1.77
article

Single-Tube Multiplex PCR-SSP for the Detection of RHD Variant Alleles Commonly Found in Serologically D− Phenotype Individuals in a Thai Population

Amornrat Romphruk, Chanvit Leelayuwat, Piyapong Simtong, Ornuma Pittayabumrung
article en
1 citations

Abstract

This study successfully established a simple and reliable molecular diagnostic platform for analyzing <i>RHD</i> variant alleles commonly found in serologically D- phenotype individuals in a Thai population. This technique could enable broader <i>RHD*01EL.01</i> (Asian-type DEL) analyses in high-prevalence areas such as Thailand and other countries in East and Southeast Asia, serving as an example for blood bank routine settings.

Transfusion Medicine and HemotherapyVol. 52(3)
Khon Kaen University (TH)
Khon Kaen University
Openalex Percentile: Top 19%
Blood groups and transfusion
1.77
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