Study of the Biomechanical and Histological Properties of the Thoracic Aorta of Diabetic Rats and Exposed to Cigarette Smoke

The biomechanical properties related to resistance are lower in DSG than in SG while elasticity, histological changes related to collagen fiber, elastic fiber, and inflammatory process, and MMP-9 activity of the aortic wall of rats do not show differences between CG and DG, SG, and DSG. Based on the methodology employed in this study, it appears that the thoracic aorta is resilient against aneurysm development.

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Publication Details

Journal
Journal of Vascular Research
Published
2025-02-13
DOI
https://doi.org/10.1159/000543322
Primary Topic
Aortic aneurysm repair treatments
Type
article
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article

Study of the Biomechanical and Histological Properties of the Thoracic Aorta of Diabetic Rats and Exposed to Cigarette Smoke

Felipe Trajano de Freitas Barão, Gina Camillo Silvestre, Erasmo Simão da Silva, Alexandre Queiroz Silva
Journal of Vascular Research
Aortic aneurysm repair treatments
article

Study of the Biomechanical and Histological Properties of the Thoracic Aorta of Diabetic Rats and Exposed to Cigarette Smoke

Felipe Trajano de Freitas Barão, Gina Camillo Silvestre, Erasmo Simão da Silva, Alexandre Queiroz Silva
article en

Abstract

The biomechanical properties related to resistance are lower in DSG than in SG while elasticity, histological changes related to collagen fiber, elastic fiber, and inflammatory process, and MMP-9 activity of the aortic wall of rats do not show differences between CG and DG, SG, and DSG. Based on the methodology employed in this study, it appears that the thoracic aorta is resilient against aneurysm development.

Journal of Vascular ResearchVol. 62(3)
Universidade de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 96%
Aortic aneurysm repair treatments
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Study of the Biomechanical and Histological Properties of the Thoracic Aorta of Diabetic Rats and Exposed to Cigarette Smoke — Felipe Trajano de Freitas Barão, Gina Camillo Silvestre, et al. · Journal of Vascular Research (2025) | TGRS Research Map | TGRS